Endocrine Abstracts

Objectives: Maternal metabolism has a major impact on foetal growth, and the risk of developing obesity, cardiovascular disease and diabetes in later life. Identification of maternal metabolic parameters in early pregnancy that predict birth weight (BW), is pivotal in the prevention of these diseases. We evaluated whether maternal triglyceride (TG) or fructosamine levels in early pregnancy, as possible reflectors of maternal insulin resistance (IR), could predominantly contrib...

Introduction: A rare cause of hypoglycemia is non-islet cell tumor hypoglycemia (NICTH), a paraneoplastic syndrome caused by tumoral overexpression of insulin-like growth factor 2 (IGF-2) and pro-IGF-2.Case presentation: : A 57-year old woman presented with odd behavior each morning that improved after breakfast and extensive weight loss (13 kg in 3 years). The patient was hypoglycemic (2.6 mmol/l) with low insulin levels (<1.39 pmol/l) and C-peptide...

Background: An increasing number of people with type 1 diabetes (TlD) have co-existing insulin resistance (IR). Our goal was to investigate whether IR is associated with continuous glucose monitor (CGM)-derived parameters (glucometrics) such as time in range (TIR), time above range (TAR), time below range (TBR) and glycaemic variability (CV).Methods: This is a retrospective analysis of two separate clinical studies (NCT0...